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Integrated Single-Cell and Spatial Transcriptomics Reveal Cell-Type-Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust
Integrated Single-Cell and Spatial Transcriptomics Reveal Cell-Type-Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust
Southern corn rust (SCR), caused by Puccinia polysora Underw. (P. polysora), poses a significant threat to maize production, yet the cell-type-specific defense mechanisms remain insufficiently characterized. To address this, we integrated single-nucleus RNA sequencing (snRNA-seq) and spatial transcriptomic sequencing (stRNA-seq) to elucidate the cell-type-specific transcriptional dynamics in maize leaves during early infection with P. polysora.

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