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Monday, 08-02-2021 | 06:02
Genome editing tool known as TALEN was found to be 5 times more efficient than CRISPR-Cas9 at locating and editing genes in the densely-packed DNA called heterochromatin. Thus, it has more potential to address genetic defects in the heterochromatin such as sickle cell anemia,beta-thalassemia, fragile X syndrome, and others. According to the article published in Nature, the researchers from the University of Illinois at Urbana−Champaign used single-molecule imaging to observe the performance of genome-editing proteins in mammalian cells.
