Study Finds Key Defense Strategy in Rice Against Blast Disease

Update date: 07 November 2025
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In a study conducted by researchers from Yunnan Agricultural University and partners, they found that overexpressing a fungal effector genePWL2, in rice can boost the plant's resistance against blast disease caused by Magnaporthe oryzae. When introduced into rice, PWL2 helped strengthen the plant's immune response and revealed a previously unknown defense mechanism in rice.

The study showed that transgenic rice lines expressing PWL2 developed smaller lesions and lower disease levels compared to non-transgenic plants. During the early stages of infection, salicylic acid (SA), a hormone that triggers plant defense, activated key immune genes, but they were found to become less active as the infection progressed. The study confirmed that SA plays a crucial role in helping rice resist M. oryzae.

The researchers concluded that rice plants use a temporal decoupling of SA-dependent and RNAi-mediated defenses against rice blast disease. Early resistance is controlled by SA-dependent defenses, while defense during the late stage relies on siRNA-mediated defense dominance. The study offers new insight into how rice uses multiple defense systems to fight fungal infections and could help in developing disease-resistant crop varieties in the future.

For more information, read the study from MPDI.

See https://www.isaaa.org/kc/cropbiotechupdate/article/default.asp?ID=21579

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